This repository contains the R code used to reproduce the results in the manuscript:

Massively parallel quantification of substrate turnover defines protease subsite cooperativity Rajani Kanth Gudipati, Dimos Gaidatzis, Jan Seebacher, Sandra Muehlhaeusser, Georg Kempf, Simone Cavadini, Daniel Hess, Charlotte Soneson and Helge Großhans

This R script determineSpecificity_dpp4.r reproduces the figures and tables related to the inference of the enzyme specificity of DPP4. The analysis of the DPF-3 experiment can be performed by replacing the DPP4 peptide log2 fold changes by the DPF-3 peptide log2 fold changes within the script (see comments in the script).