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MicrobiotaProcess: A comprehensive R package for deep mining microbiome

The graphical abstract

The graphical abstract

If you use this work in published research, please cite:

Shuangbin Xu, Li Zhan, Wenli Tang, Qianwen Wang, Zehan Dai, Lang Zhou, Tingze Feng, Meijun Chen, Tianzhi Wu, Erqiang Hu, Guangchuang Yu*. MicrobiotaProcess: A comprehensive R package for deep mining microbiome. The Innovation. 2023, 4(2):100388. doi: 10.1016/j.xinn.2023.100388.

This repo contains source code and data to produce Supplementary Material of the above paper.

To compile the supplementary_file_A.pdf and supplementary_file_B.pdf, please run the following command in R:

rmarkdown::render("supplementary_file_A.Rmd")
rmarkdown::render("supplementary_file_B.Rmd")

Here is the output of sessioninfo::session_info() on the system on which this document was compiled:

## ─ Session info ──────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────
##  setting  value
##  version  R version 4.2.0 (2022-04-22)
##  os       Ubuntu 18.04.4 LTS
##  system   x86_64, linux-gnu
##  ui       X11
##  language (EN)
##  collate  en_US.UTF-8
##  ctype    en_US.UTF-8
##  tz       Asia/Shanghai
##  date     2023-02-08
##  pandoc   2.9.2 @ /usr/bin/ (via rmarkdown)
## 
## ─ Packages ──────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────
##  package                  * version    date (UTC) lib source
##  ade4                       1.7-19     2022-04-19 [1] CRAN (R 4.2.0)
##  ANCOMBC                  * 1.6.2      2022-06-26 [1] Bioconductor
##  AnnotationDbi              1.58.0     2022-04-26 [1] Bioconductor
##  AnnotationHub              3.4.0      2022-04-26 [1] Bioconductor
##  ape                        5.6-3      2022-10-30 [1] Github (emmanuelparadis/ape@090e82c)
##  aplot                    * 0.1.8      2022-11-17 [1] local
##  assertthat                 0.2.1      2019-03-21 [1] CRAN (R 4.2.0)
##  attempt                    0.3.1      2020-05-03 [1] CRAN (R 4.2.0)
##  backports                  1.4.1      2021-12-13 [1] CRAN (R 4.2.0)
##  base64enc                  0.1-3      2015-07-28 [1] CRAN (R 4.2.0)
##  beachmat                   2.12.0     2022-04-26 [1] Bioconductor
##  beeswarm                   0.4.0      2021-06-01 [1] CRAN (R 4.2.0)
##  Biobase                  * 2.56.0     2022-04-26 [1] Bioconductor
##  BiocFileCache              2.4.0      2022-04-26 [1] Bioconductor
##  BiocGenerics             * 0.42.0     2022-04-26 [1] Bioconductor
##  BiocManager                1.30.18    2022-05-18 [1] CRAN (R 4.2.0)
##  BiocNeighbors              1.14.0     2022-04-26 [1] Bioconductor
##  BiocParallel               1.30.3     2022-06-05 [1] Bioconductor
##  BiocSingular               1.12.0     2022-04-26 [1] Bioconductor
##  BiocVersion                3.15.2     2022-03-29 [1] Bioconductor
##  biomformat                 1.24.0     2022-04-26 [1] Bioconductor
##  Biostrings               * 2.64.1     2022-08-18 [1] Bioconductor
##  bit                        4.0.4      2020-08-04 [1] CRAN (R 4.2.0)
##  bit64                      4.0.5      2020-08-30 [1] CRAN (R 4.2.0)
##  bitops                     1.0-7      2021-04-24 [1] CRAN (R 4.2.0)
##  blob                       1.2.3      2022-04-10 [1] CRAN (R 4.2.0)
##  boot                       1.3-28     2021-05-03 [1] CRAN (R 4.2.0)
##  broom                    * 1.0.0      2022-07-01 [1] CRAN (R 4.2.0)
##  bslib                      0.4.0      2022-07-16 [1] CRAN (R 4.2.0)
##  cachem                     1.0.6      2021-08-19 [1] CRAN (R 4.2.0)
##  caTools                    1.18.2     2021-03-28 [1] CRAN (R 4.2.0)
##  cellranger                 1.1.0      2016-07-27 [1] CRAN (R 4.2.0)
##  checkmate                  2.1.0      2022-04-21 [1] CRAN (R 4.2.0)
##  class                      7.3-20     2022-01-16 [1] CRAN (R 4.2.0)
##  cli                        3.4.1      2022-09-23 [1] CRAN (R 4.2.0)
##  clue                       0.3-61     2022-05-30 [1] CRAN (R 4.2.0)
##  cluster                    2.1.3      2022-03-28 [1] CRAN (R 4.2.0)
##  clusterProfiler          * 4.5.2      2022-09-06 [1] Bioconductor
##  codetools                  0.2-18     2020-11-04 [1] CRAN (R 4.2.0)
##  coin                     * 1.4-2      2021-10-08 [1] CRAN (R 4.2.0)
##  colorspace                 2.0-3      2022-02-21 [1] CRAN (R 4.2.0)
##  config                     0.3.1      2020-12-17 [1] CRAN (R 4.2.0)
##  crayon                     1.5.1      2022-03-26 [1] CRAN (R 4.2.0)
##  curatedMetagenomicData   * 3.4.2      2022-05-19 [1] Bioconductor
##  curl                       4.3.2      2021-06-23 [1] CRAN (R 4.2.0)
##  data.table                 1.14.2     2021-09-27 [1] CRAN (R 4.2.0)
##  DBI                        1.1.3      2022-06-18 [1] CRAN (R 4.2.0)
##  dbplyr                     2.2.1      2022-06-27 [1] CRAN (R 4.2.0)
##  DECIPHER                   2.24.0     2022-04-26 [1] Bioconductor
##  decontam                   1.16.0     2022-04-26 [1] Bioconductor
##  DelayedArray               0.22.0     2022-04-26 [1] Bioconductor
##  DelayedMatrixStats         1.18.0     2022-04-26 [1] Bioconductor
##  deldir                     1.0-6      2021-10-23 [1] CRAN (R 4.2.0)
##  desc                       1.4.2      2022-09-08 [1] CRAN (R 4.2.0)
##  DescTools                  0.99.46    2022-09-01 [1] CRAN (R 4.2.0)
##  digest                     0.6.30     2022-10-18 [1] CRAN (R 4.2.0)
##  DirichletMultinomial       1.38.0     2022-04-26 [1] Bioconductor
##  DO.db                      2.9        2022-09-06 [1] Bioconductor
##  doParallel                 1.0.17     2022-02-07 [1] CRAN (R 4.2.0)
##  doRNG                      1.8.2      2020-01-27 [1] CRAN (R 4.2.0)
##  DOSE                       3.23.2.001 2022-09-06 [1] Bioconductor
##  downloader                 0.4        2015-07-09 [1] CRAN (R 4.2.0)
##  dplyr                      1.0.10     2022-09-01 [1] CRAN (R 4.2.0)
##  DT                         0.25       2022-09-12 [1] CRAN (R 4.2.0)
##  e1071                      1.7-11     2022-06-07 [1] CRAN (R 4.2.0)
##  edgeR                    * 3.38.4     2022-08-07 [1] Bioconductor
##  ellipsis                   0.3.2      2021-04-29 [1] CRAN (R 4.2.0)
##  energy                     1.7-10     2022-04-19 [1] CRAN (R 4.2.0)
##  enrichplot               * 1.17.0.995 2022-09-06 [1] Bioconductor
##  evaluate                   0.16       2022-08-09 [1] CRAN (R 4.2.0)
##  Exact                      3.1        2021-11-26 [1] CRAN (R 4.2.0)
##  ExperimentHub              2.4.0      2022-04-26 [1] Bioconductor
##  expm                       0.999-6    2021-01-13 [1] CRAN (R 4.2.0)
##  fansi                      1.0.3      2022-03-24 [1] CRAN (R 4.2.0)
##  farver                     2.1.1      2022-07-06 [1] CRAN (R 4.2.0)
##  fastmap                    1.1.0      2021-01-25 [1] CRAN (R 4.2.0)
##  fastmatch                  1.1-3      2021-07-23 [1] CRAN (R 4.2.0)
##  fBasics                    4021.92    2022-08-08 [1] CRAN (R 4.2.0)
##  fgsea                      1.22.0     2022-04-26 [1] Bioconductor
##  filelock                   1.0.2      2018-10-05 [1] CRAN (R 4.2.0)
##  forcats                  * 0.5.1      2021-01-27 [1] CRAN (R 4.2.0)
##  foreach                    1.5.2      2022-02-02 [1] CRAN (R 4.2.0)
##  foreign                    0.8-82     2022-01-16 [1] CRAN (R 4.2.0)
##  Formula                    1.2-4      2020-10-16 [1] CRAN (R 4.2.0)
##  fs                         1.5.2      2021-12-08 [1] CRAN (R 4.2.0)
##  generics                   0.1.3      2022-07-05 [1] CRAN (R 4.2.0)
##  GenomeInfoDb             * 1.32.4     2022-09-06 [1] Bioconductor
##  GenomeInfoDbData           1.2.8      2022-04-28 [1] Bioconductor
##  GenomicRanges            * 1.48.0     2022-04-26 [1] Bioconductor
##  ggbeeswarm                 0.6.0      2017-08-07 [1] CRAN (R 4.2.0)
##  ggforce                    0.3.3      2021-03-05 [1] CRAN (R 4.2.0)
##  ggfun                      0.0.6      2022-08-30 [1] local
##  ggnewscale               * 0.4.7      2022-03-25 [1] CRAN (R 4.2.0)
##  ggplot2                  * 3.4.0      2022-11-04 [1] CRAN (R 4.2.0)
##  ggplotify                  0.1.0      2021-09-02 [1] CRAN (R 4.2.0)
##  ggpp                     * 0.4.5      2022-09-30 [1] CRAN (R 4.2.0)
##  ggraph                     2.0.6      2022-08-08 [1] CRAN (R 4.2.0)
##  ggrepel                  * 0.9.1      2021-01-15 [1] CRAN (R 4.2.0)
##  ggsignif                   0.6.3      2021-09-09 [1] CRAN (R 4.2.0)
##  ggstar                     1.0.3      2021-12-03 [1] CRAN (R 4.2.0)
##  ggtree                   * 3.7.1      2022-11-10 [1] Bioconductor
##  ggtreeExtra              * 1.9.1.990  2022-11-24 [1] Bioconductor
##  ggupset                  * 0.3.0      2020-05-05 [1] CRAN (R 4.2.0)
##  ggVennDiagram            * 1.2.0      2021-10-22 [1] CRAN (R 4.2.0)
##  gld                        2.6.5      2022-06-29 [1] CRAN (R 4.2.0)
##  glmnet                   * 4.1-4      2022-04-15 [1] CRAN (R 4.2.0)
##  glue                       1.6.2      2022-02-24 [1] CRAN (R 4.2.0)
##  GO.db                      3.15.0     2022-09-06 [1] Bioconductor
##  golem                      0.3.5      2022-10-18 [1] CRAN (R 4.2.0)
##  GOSemSim                   2.22.0     2022-04-26 [1] Bioconductor
##  gplots                     3.1.3      2022-04-25 [1] CRAN (R 4.2.0)
##  graphlayouts               0.8.0      2022-01-03 [1] CRAN (R 4.2.0)
##  gridExtra                  2.3        2017-09-09 [1] CRAN (R 4.2.0)
##  gridGraphics               0.5-1      2020-12-13 [1] CRAN (R 4.2.0)
##  gsl                        2.1-7.1    2021-11-02 [1] CRAN (R 4.2.0)
##  gson                       0.0.8      2022-08-20 [1] CRAN (R 4.2.0)
##  gtable                     0.3.1      2022-09-01 [1] CRAN (R 4.2.0)
##  gtools                     3.9.3      2022-07-11 [1] CRAN (R 4.2.0)
##  GUniFrac                 * 1.7        2022-10-23 [1] CRAN (R 4.2.0)
##  highr                      0.9        2021-04-16 [1] CRAN (R 4.2.0)
##  Hmisc                      4.7-0      2022-04-19 [1] CRAN (R 4.2.0)
##  hms                        1.1.1      2021-09-26 [1] CRAN (R 4.2.0)
##  htmlTable                  2.4.1      2022-07-07 [1] CRAN (R 4.2.0)
##  htmltools                  0.5.3      2022-07-18 [1] CRAN (R 4.2.0)
##  htmlwidgets                1.5.4      2021-09-08 [1] CRAN (R 4.2.0)
##  httpuv                     1.6.6      2022-09-08 [1] CRAN (R 4.2.0)
##  httr                       1.4.4      2022-08-17 [1] CRAN (R 4.2.0)
##  igraph                   * 1.3.4      2022-07-19 [1] CRAN (R 4.2.0)
##  interactiveDisplayBase     1.34.0     2022-04-26 [1] Bioconductor
##  interp                     1.1-3      2022-07-13 [1] CRAN (R 4.2.0)
##  IRanges                  * 2.30.1     2022-08-18 [1] Bioconductor
##  irlba                      2.3.5      2021-12-06 [1] CRAN (R 4.2.0)
##  iterators                  1.0.14     2022-02-05 [1] CRAN (R 4.2.0)
##  jpeg                       0.1-9      2021-07-24 [1] CRAN (R 4.2.0)
##  jquerylib                  0.1.4      2021-04-26 [1] CRAN (R 4.2.0)
##  jsonlite                   1.8.0      2022-02-22 [1] CRAN (R 4.2.0)
##  KEGGREST                   1.36.3     2022-07-12 [1] Bioconductor
##  KernSmooth                 2.23-20    2021-05-03 [1] CRAN (R 4.2.0)
##  knitr                      1.39       2022-04-26 [1] CRAN (R 4.2.0)
##  later                      1.3.0      2021-08-18 [1] CRAN (R 4.2.0)
##  lattice                    0.20-45    2021-09-22 [1] CRAN (R 4.2.0)
##  latticeExtra               0.6-30     2022-07-04 [1] CRAN (R 4.2.0)
##  lazyeval                   0.2.2      2019-03-15 [1] CRAN (R 4.2.0)
##  libcoin                    1.0-9      2021-09-27 [1] CRAN (R 4.2.0)
##  lifecycle                  1.0.3      2022-10-07 [1] CRAN (R 4.2.0)
##  limma                    * 3.52.3     2022-09-11 [1] Bioconductor
##  lme4                       1.1-30     2022-07-08 [1] CRAN (R 4.2.0)
##  lmerTest                   3.1-3      2020-10-23 [1] CRAN (R 4.2.0)
##  lmom                       2.9        2022-05-29 [1] CRAN (R 4.2.0)
##  locfit                     1.5-9.6    2022-07-11 [1] CRAN (R 4.2.0)
##  magrittr                   2.0.3      2022-03-30 [1] CRAN (R 4.2.0)
##  MASS                       7.3-57     2022-04-22 [1] CRAN (R 4.2.0)
##  Matrix                   * 1.4-1      2022-03-23 [1] CRAN (R 4.2.0)
##  MatrixGenerics           * 1.8.1      2022-06-26 [1] Bioconductor
##  matrixStats              * 0.62.0     2022-04-19 [1] CRAN (R 4.2.0)
##  memoise                    2.0.1      2021-11-26 [1] CRAN (R 4.2.0)
##  metagenomeSeq            * 1.38.0     2022-04-26 [1] Bioconductor
##  mgcv                       1.8-40     2022-03-29 [1] CRAN (R 4.2.0)
##  mia                        1.4.0      2022-04-26 [1] Bioconductor
##  microbiome                 1.18.0     2022-04-26 [1] Bioconductor
##  MicrobiomeProfiler       * 1.1.0      2022-11-08 [1] Bioconductor
##  MicrobiomeStat           * 1.1        2022-01-24 [1] CRAN (R 4.2.0)
##  MicrobiotaProcess        * 1.11.4     2023-01-30 [1] Bioconductor
##  mime                       0.12       2021-09-28 [1] CRAN (R 4.2.0)
##  minqa                      1.2.4      2014-10-09 [1] CRAN (R 4.2.0)
##  modeest                    2.4.0      2019-11-18 [1] CRAN (R 4.2.0)
##  modeltools                 0.2-23     2020-03-05 [1] CRAN (R 4.2.0)
##  multcomp                   1.4-19     2022-04-26 [1] CRAN (R 4.2.0)
##  MultiAssayExperiment       1.22.0     2022-04-26 [1] Bioconductor
##  multtest                   2.52.0     2022-04-26 [1] Bioconductor
##  munsell                    0.5.0      2018-06-12 [1] CRAN (R 4.2.0)
##  mvtnorm                    1.1-3      2021-10-08 [1] CRAN (R 4.2.0)
##  nlme                       3.1-158    2022-06-15 [1] CRAN (R 4.2.0)
##  nloptr                     2.0.3      2022-05-26 [1] CRAN (R 4.2.0)
##  nnet                       7.3-17     2022-01-16 [1] CRAN (R 4.2.0)
##  numDeriv                   2016.8-1.1 2019-06-06 [1] CRAN (R 4.2.0)
##  patchwork                * 1.1.2      2022-08-19 [1] CRAN (R 4.2.0)
##  permute                    0.9-7      2022-01-27 [1] CRAN (R 4.2.0)
##  phyloseq                   1.40.0     2022-04-26 [1] Bioconductor
##  pillar                     1.8.1      2022-08-19 [1] CRAN (R 4.2.0)
##  pkgconfig                  2.0.3      2019-09-22 [1] CRAN (R 4.2.0)
##  pkgload                    1.3.0      2022-06-27 [1] CRAN (R 4.2.0)
##  plyr                       1.8.7      2022-03-24 [1] CRAN (R 4.2.0)
##  png                        0.1-7      2013-12-03 [1] CRAN (R 4.2.0)
##  polyclip                   1.10-0     2019-03-14 [1] CRAN (R 4.2.0)
##  preprocessCore             1.58.0     2022-04-26 [1] Bioconductor
##  pROC                     * 1.18.0     2021-09-03 [1] CRAN (R 4.2.0)
##  promises                   1.2.0.1    2021-02-11 [1] CRAN (R 4.2.0)
##  proxy                      0.4-27     2022-06-09 [1] CRAN (R 4.2.0)
##  purrr                      0.3.5      2022-10-06 [1] CRAN (R 4.2.0)
##  qvalue                     2.28.0     2022-04-26 [1] Bioconductor
##  R6                         2.5.1      2021-08-19 [1] CRAN (R 4.2.0)
##  randomForest             * 4.7-1.1    2022-05-23 [1] CRAN (R 4.2.0)
##  rappdirs                   0.3.3      2021-01-31 [1] CRAN (R 4.2.0)
##  rbibutils                  2.2.9      2022-08-15 [1] CRAN (R 4.2.0)
##  RColorBrewer             * 1.1-3      2022-04-03 [1] CRAN (R 4.2.0)
##  Rcpp                       1.0.9      2022-07-08 [1] CRAN (R 4.2.0)
##  RCurl                      1.98-1.8   2022-07-30 [1] CRAN (R 4.2.0)
##  Rdpack                     2.4        2022-07-20 [1] CRAN (R 4.2.0)
##  readr                      2.1.2      2022-01-30 [1] CRAN (R 4.2.0)
##  readxl                     1.4.1      2022-08-17 [1] CRAN (R 4.2.0)
##  reshape2                   1.4.4      2020-04-09 [1] CRAN (R 4.2.0)
##  rhdf5                      2.40.0     2022-04-26 [1] Bioconductor
##  rhdf5filters               1.8.0      2022-04-26 [1] Bioconductor
##  Rhdf5lib                   1.18.2     2022-05-15 [1] Bioconductor
##  rlang                      1.0.6      2022-09-24 [1] CRAN (R 4.2.0)
##  rmarkdown                  2.15       2022-08-16 [1] CRAN (R 4.2.0)
##  rmutil                     1.1.9      2022-03-01 [1] CRAN (R 4.2.0)
##  rngtools                   1.5.2      2021-09-20 [1] CRAN (R 4.2.0)
##  rootSolve                  1.8.2.3    2021-09-29 [1] CRAN (R 4.2.0)
##  roxygen2                   7.2.1      2022-07-18 [1] CRAN (R 4.2.0)
##  rpart                      4.1.16     2022-01-24 [1] CRAN (R 4.2.0)
##  rprojroot                  2.0.3      2022-04-02 [1] CRAN (R 4.2.0)
##  RSQLite                    2.2.17     2022-09-10 [1] CRAN (R 4.2.0)
##  rstudioapi                 0.13       2020-11-12 [1] CRAN (R 4.2.0)
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##  Rtsne                      0.16       2022-04-17 [1] CRAN (R 4.2.0)
##  RVenn                      1.1.0      2019-07-18 [1] CRAN (R 4.2.0)
##  S4Vectors                * 0.34.0     2022-04-26 [1] Bioconductor
##  sandwich                   3.0-2      2022-06-15 [1] CRAN (R 4.2.0)
##  sass                       0.4.2      2022-07-16 [1] CRAN (R 4.2.0)
##  ScaledMatrix               1.4.0      2022-04-26 [1] Bioconductor
##  scales                     1.2.1      2022-08-20 [1] CRAN (R 4.2.0)
##  scater                     1.24.0     2022-04-26 [1] Bioconductor
##  scatterpie                 0.1.7      2022-09-02 [1] local
##  scuttle                    1.6.3      2022-08-23 [1] Bioconductor
##  sessioninfo                1.2.2      2021-12-06 [1] CRAN (R 4.2.0)
##  shadowtext               * 0.1.2      2022-04-22 [1] CRAN (R 4.2.0)
##  shape                      1.4.6      2021-05-19 [1] CRAN (R 4.2.0)
##  shiny                      1.7.2      2022-07-19 [1] CRAN (R 4.2.0)
##  shinycustomloader          0.9.0      2018-03-27 [1] CRAN (R 4.2.0)
##  shinyWidgets               0.7.4      2022-10-05 [1] CRAN (R 4.2.0)
##  SingleCellExperiment     * 1.18.0     2022-04-26 [1] Bioconductor
##  sparseMatrixStats          1.8.0      2022-04-26 [1] Bioconductor
##  spatial                    7.3-15     2022-01-16 [1] CRAN (R 4.2.0)
##  stable                     1.1.6      2022-03-02 [1] CRAN (R 4.2.0)
##  stabledist                 0.7-1      2016-09-12 [1] CRAN (R 4.2.0)
##  statip                     0.2.3      2019-11-17 [1] CRAN (R 4.2.0)
##  statmod                    1.4.37     2022-08-12 [1] CRAN (R 4.2.0)
##  stringi                    1.7.8      2022-07-11 [1] CRAN (R 4.2.0)
##  stringr                    1.4.1      2022-08-20 [1] CRAN (R 4.2.0)
##  SummarizedExperiment     * 1.26.1     2022-04-29 [1] Bioconductor
##  survival                 * 3.3-1      2022-03-03 [1] CRAN (R 4.2.0)
##  TH.data                    1.1-1      2022-04-26 [1] CRAN (R 4.2.0)
##  tibble                     3.1.8      2022-07-22 [1] CRAN (R 4.2.0)
##  tidybulk                 * 1.8.2      2022-09-29 [1] Bioconductor
##  tidygraph                  1.2.2      2022-08-22 [1] CRAN (R 4.2.0)
##  tidyr                      1.2.1      2022-09-08 [1] CRAN (R 4.2.0)
##  tidyselect                 1.2.0      2022-10-10 [1] CRAN (R 4.2.0)
##  tidytree                   0.4.2      2022-12-18 [1] CRAN (R 4.2.0)
##  timeDate                   4021.104   2022-07-19 [1] CRAN (R 4.2.0)
##  timeSeries                 4021.104   2022-07-17 [1] CRAN (R 4.2.0)
##  treeio                     1.21.3     2022-10-30 [1] Bioconductor
##  TreeSummarizedExperiment * 2.4.0      2022-04-26 [1] Bioconductor
##  tweenr                     1.0.2      2021-03-23 [1] CRAN (R 4.2.0)
##  tzdb                       0.3.0      2022-03-28 [1] CRAN (R 4.2.0)
##  usethis                    2.1.6      2022-05-25 [1] CRAN (R 4.2.0)
##  utf8                       1.2.2      2021-07-24 [1] CRAN (R 4.2.0)
##  vctrs                      0.5.0      2022-10-22 [1] CRAN (R 4.2.0)
##  vegan                      2.6-2      2022-04-17 [1] CRAN (R 4.2.0)
##  vipor                      0.4.5      2017-03-22 [1] CRAN (R 4.2.0)
##  viridis                    0.6.2      2021-10-13 [1] CRAN (R 4.2.0)
##  viridisLite                0.4.1      2022-08-22 [1] CRAN (R 4.2.0)
##  withr                      2.5.0      2022-03-03 [1] CRAN (R 4.2.0)
##  Wrench                     1.14.0     2022-04-26 [1] Bioconductor
##  xfun                       0.32       2022-08-10 [1] CRAN (R 4.2.0)
##  xml2                       1.3.3      2021-11-30 [1] CRAN (R 4.2.0)
##  xtable                     1.8-4      2019-04-21 [1] CRAN (R 4.2.0)
##  XVector                  * 0.36.0     2022-04-26 [1] Bioconductor
##  yaml                       2.3.5      2022-02-21 [1] CRAN (R 4.2.0)
##  yulab.utils                0.0.5      2022-06-30 [1] CRAN (R 4.2.0)
##  zlibbioc                   1.42.0     2022-04-26 [1] Bioconductor
##  zoo                        1.8-10     2022-04-15 [1] CRAN (R 4.2.0)
## 
##  [1] /mnt/d/UbuntuApps/R/4.2.0/lib/R/library
## 
## ─────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────────

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