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Signal peptide discrimination using a HMM with known states

A classifier that is able to detect signal peptide sequences in a proteom, using two HMMs that are trained with annotated sequences (known states).

Instructions

  1. Load training data:

df = fill_train_df()

  1. To run cross validation on training data use:

cross_validate(df, validations = 5, write = True)

  1. To run a performance test on a proteome (labelled by SignalP 4.1) use:

test_proteom(df, 'ecoli', stopidx = 3, write = True)

All results are stored in the 'res' folder.

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Classifying signal peptides

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