This repository is used to carry out a generalized meta-analysis for any outcome.
This is used for establishing dose-repose DR relationship between Physical-Activity and disease outcomes/causes. At the moment, we are dealing with:
- All-cause cancer
- All-cause cvd
- All-cause dementia
- All-cause mortality
- Alzheimer's disease
- Bladder cancer
- Breast cancer
- Colon cancer
- Coronary heart disease
- Depression
- Elevated depressive symptoms
- Endometrial cancer
- Esophageal cancer
- Gastric cardia cancer
- Head and neck cancer
- Heart failure
- Kidney cancer
- Liver cancer
- Lung cancer
- Major depression
- Myeloid leukemia
- Myeloma
- Parkinson's disease
- Prostate cancer
- Rectum cancer
- Stroke
- Vascular dementia
The main script which runs the analysis, and saves the outputs (in CSV files and figures) is stored at: script/master_script.R
We have written a script which reads the output from meta-analyis for:
- Depression
- Elevated depressive symptoms
- Major depression
And plots them in script/plot-depression-outcomes
We have developed an interactive application to show individual dose-response curve for all the outcomes. You may see it here: https://shiny.mrc-epid.cam.ac.uk/meta-analyses-physical-activity/
The code for this app sits in a separate repo at: https://github.com/meta-analyses/meta-analysis-shiny