v2.4.6 readying for CRAN submission

[n8thangreen]

Since the last PR, all I've done is bump up the versions for things really..

[giabaio]

I think the installation throws a warning (for the indirect dependency to the orphaned package) + a few notes (one happens all the time - it is about a folder being too large; another is about the citation file, which I've created for GitHub, but probably should be added to the .Rignore file?)

[giabaio]

In fact, this is the content of the .Rbuildignore file for the main branch, which I think works OK:

^renv$
^renv\.lock$
^.*\.Rproj$
^\.Rproj\.user$
^\.travis\.yml$
^appveyor\.yml$
^LICENSE\.md$
^_pkgdown\.yml$
^docs$
^pkgdown$
^\.httr-oauth$
^CONDUCT\.md$
^man-roxygen$
^.git
^.gitignore
^cran-comments\.md$
^README_dev\.md$
^\.github$
^inst/extdata/vaccine_jags\.RData$
^inst/extdata/statins_base\.RData$
^inst/extdata/statins_HC\.RData$
^inst/extdata/smoking_output\.RData$
^paper\.bib$
^paper\.md$
^CONTRIBUTING\.md$
^revdep$
^CRAN-SUBMISSION$
^CITATION.cff

Perhaps try and use this when you do the push?