Prevalence of chronic obstructive pulmonary disease in England from 2000 to 2019

Publication

https://doi.org/10.2147/COPD.S411739

COPD definitions

COPD Definition	Data source	Definition	Codelist
Validated COPD	Primary care (CPRD Aurum)	Algorithm 4 (specific COPD code only) from Quint JK, et al. BMJ Open 2014;4:e005540 mapped from Read v2 to SNOMED CT	copd_validated_aurum_2021-10-21.dta.csv
Quality and Outcomes Framework (QOF)1 COPD	Primary care (CPRD Aurum)	QOF v46 COPD business rules	copd_qof_v46.dta.csv
Possible undiagnosed COPD	Primary care (CPRD Aurum)	A history of tobacco smoking, At least 1 respiratory symptom (cough, dyspnoea, or sputum production), A prescription for an inhaler, AND no asthma diagnosis	smoking_status.dta.csv (smoking_status == "Current smoker" OR "Ex-smoker") copd_symptoms.dta.csv copd_meds_combined.dta.csv (groups == "lama" OR "laba" OR "lama_laba" OR "ics" OR "laba_ics" OR "triple") asthma_codes_for_current_cases_189.dta.csv (exclude if present in patient record)
Any hospital admission with COPD or emphysema as a listed diagnosis	Secondary care (Hospital Episode Statistics)	A COPD or emphysema diagnosis code anywhere in the HES record	ICD10_COPD.tsv
COPD or emphysema hospital admission (primary/secondary diagnosis)	Secondary care (Hospital Episode Statistics)	COPD or emphysema diagnosis code in the first or second position in the HES record	ICD10_COPD.tsv

Codelists

All other variable definitions can be found in /codelists in both stata and text formats.

Data management and analysis scripts

All Stata scripts used to build the datasets and complete analyses can be found in /stata.

Footnotes

1. The Quality and Outcomes Framework (QOF) is a primary care pay-for-performance scheme. General practices receive points for completing specific items of care within a certain timeframe. The proportion of maximum possible points received in a year determines the size of financial bonus received at the end of the year. ↩