10.1016j.cell.2018.04.012.ann

T1 Gene 498 517 histone deacetylase
T2 Level 628 649  drug-resistant cells
T3 Organism 533 539 ostat 
T4 Organism 866 874 patients
T5 Biomarker 795 798 vor
T6 Biomarker 795 805 vorinostat
T7 Level 975 1001 drug-resistant tumor cells
T8 Level 834 839 tumor
T9 Biomarker 941 944 vor
T10 Level 716 721 tumor
T11 Biomarker 528 538 vorinostat
T12 Condition 315 349 MAPK inhibitor-resistant melanomas
T13 Organism 808 813  mice
T14 Level 701 727 drug-resistant tumor cells
T15 Intervention 756 789 BRAF inhibitor-resistant melanoma
T16 Biomarker 941 951 vorinostat
T17 Level 622 626 ROS 
T18 Gene 11 28  mutant melanomas
T19 Level 990 995 tumor
T20 Protein 60 200 BRAF and MEK kinases almost invariably develop resistance that is frequently caused by reactivation of the mitogen activated protein kinase 
T21 Biomarker 528 531 vor
T22 Protein 314 319  MAPK
T23 Organism 261 269 patients
T24 Protein 595 611 already-elevated
T25 Biomarker 446 452 oxygen
T26 Organism 800 806 ostat 
T27 Protein 550 557 SLC7A11
T28 Organism 946 952 ostat 
R1 Relation Arg1:T23 Arg2:T22