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Higher-order motif analysis in hypergraphs

This code implements the algorithms for higher-order motif analysis proposed in https://www.nature.com/articles/s42005-022-00858-7

Abstract

A deluge of new data on real-world networks suggests that interactions among system units are not limited to pairs, but often involve a higher number of nodes. To properly encode higher-order interactions, richer mathematical frameworks such as hypergraphs are needed, where hyperedges describe interactions among an arbitrary number of nodes. Here we systematically investigate higher-order motifs, defined as small connected subgraphs in which vertices may be linked by interactions of any order, and propose an efficient algorithm to extract complete higher-order motif profiles from empirical data. We identify different families of hypergraphs, characterized by distinct higher-order connectivity patterns at the local scale. We also propose a set of measures to study the nested structure of hyperedges and provide evidences of structural reinforcement, a mechanism that associates higher strengths of higher-order interactions for the nodes that interact more at the pairwise level. Our work highlights the informative power of higher-order motifs, providing a principled way to extract higher-order fingerprints in hypergraphs at the network microscale.

Code organization

  • motifs.py contains the implementation of the baseline algorithm proposed in the paper
  • motif2.py contains the implementation of the efficient algorithm proposed in the paper
  • utils.py contains some useful functions
  • loaders.py contains the loader for the datasets (see section below)
  • hypergraph.py contains the implementation of a data structure for hypergraphs in Python and the configuration model for hypergraphs proposed by Phil Chodrow

Datasets

Please download the datasets here and extract the archive inside the main directory.

How to use custom datasets

If you wish to perform higher-order motif analysis on your own datasets, you should implement a custom loader function. This function should return a set of tuples. Each tuple represents an hyperedge, and will contain the ids of the nodes involved in a group interactions.

How to perform higher-order motif analysis

If you wish to experiment with the code, you can run analysis setting up the parameter N in the code, which specifies the order of the motifs to use for the analysis. At the moment, the only feasible orders are N=3 and N=4. The parameter ROUNDS specifies the number of samples from the configuration model. Keep in mind that ROUNDS can heavily affect the performance. A value between 10 and 20 already gives reliable results.

Acknowledgments

We thank Phil Chodrow for the code in the file hypergraph.py