diff --git a/packages/plugin-vue/src/index.ts b/packages/plugin-vue/src/index.ts
index b301a596..72f8944b 100644
--- a/packages/plugin-vue/src/index.ts
+++ b/packages/plugin-vue/src/index.ts
@@ -19,7 +19,7 @@ import {
   getSrcDescriptor,
   getTempSrcDescriptor,
 } from './utils/descriptorCache'
-import { getResolvedScript, typeDepToSFCMap } from './script'
+import { clearScriptCache, getResolvedScript, typeDepToSFCMap } from './script'
 import { transformMain } from './main'
 import { handleHotUpdate, handleTypeDepChange } from './handleHotUpdate'
 import { transformTemplateAsModule } from './template'
@@ -361,5 +361,8 @@ export default function vuePlugin(rawOptions: Options = {}): Plugin<Api> {
         }
       }
     },
+    buildEnd() {
+      clearScriptCache()
+    },
   }
 }
diff --git a/packages/plugin-vue/src/script.ts b/packages/plugin-vue/src/script.ts
index e0e821c3..4c97a0a6 100644
--- a/packages/plugin-vue/src/script.ts
+++ b/packages/plugin-vue/src/script.ts
@@ -4,8 +4,8 @@ import { cache as descriptorCache } from './utils/descriptorCache'
 import type { ResolvedOptions } from '.'
 
 // ssr and non ssr builds would output different script content
-const clientCache = new WeakMap<SFCDescriptor, SFCScriptBlock | null>()
-const ssrCache = new WeakMap<SFCDescriptor, SFCScriptBlock | null>()
+let clientCache = new WeakMap<SFCDescriptor, SFCScriptBlock | null>()
+let ssrCache = new WeakMap<SFCDescriptor, SFCScriptBlock | null>()
 
 export const typeDepToSFCMap = new Map<string, Set<string>>()
 
@@ -32,6 +32,11 @@ export function setResolvedScript(
   ;(ssr ? ssrCache : clientCache).set(descriptor, script)
 }
 
+export function clearScriptCache(): void {
+  clientCache = new WeakMap()
+  ssrCache = new WeakMap()
+}
+
 // Check if we can use compile template as inlined render function
 // inside <script setup>. This can only be done for build because
 // inlined template cannot be individually hot updated.