diff --git a/src/index.js b/src/index.js
index 4f92e02b..c89dc1a2 100644
--- a/src/index.js
+++ b/src/index.js
@@ -5,7 +5,7 @@ import {cleanup} from './pure'
 // this ensures that tests run in isolation from each other
 // if you don't like this then either import the `pure` module
 // or set the RTL_SKIP_AUTO_CLEANUP env variable to 'true'.
-if (!process.env.RTL_SKIP_AUTO_CLEANUP) {
+if (typeof process === "undefined" || !process.env?.RTL_SKIP_AUTO_CLEANUP) {
   // ignore teardown() in code coverage because Jest does not support it
   /* istanbul ignore else */
   if (typeof afterEach === 'function') {