diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index aac5df14883678..4198b4ee62b9c5 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -132,3 +132,6 @@ iso4217!=1.10.20220401
 
 # Pandas 1.4.4 has issues with wheels om armhf + Py3.10
 pandas==1.4.3
+
+# pyopenssl 22.1.0 requires pycryptography > 38 and we have 37
+pyopenssl==22.0.0
diff --git a/script/gen_requirements_all.py b/script/gen_requirements_all.py
index d0eb830f0889d1..eec89d4210c0cf 100755
--- a/script/gen_requirements_all.py
+++ b/script/gen_requirements_all.py
@@ -142,6 +142,9 @@
 
 # Pandas 1.4.4 has issues with wheels om armhf + Py3.10
 pandas==1.4.3
+
+# pyopenssl 22.1.0 requires pycryptography > 38 and we have 37
+pyopenssl==22.0.0
 """
 
 IGNORE_PRE_COMMIT_HOOK_ID = (