diff --git a/.changeset/gold-pears-march.md b/.changeset/gold-pears-march.md
new file mode 100644
index 00000000000..61c37d94328
--- /dev/null
+++ b/.changeset/gold-pears-march.md
@@ -0,0 +1,5 @@
+---
+"@apollo/client": patch
+---
+
+Don’t prompt for DevTools installation for browser extension page
diff --git a/src/core/ApolloClient.ts b/src/core/ApolloClient.ts
index 42daf602226..05e713d520a 100644
--- a/src/core/ApolloClient.ts
+++ b/src/core/ApolloClient.ts
@@ -313,7 +313,8 @@ export class ApolloClient<TCacheShape> implements DataProxy {
           typeof window !== "undefined" &&
           window.document &&
           window.top === window.self &&
-          !(window as any).__APOLLO_DEVTOOLS_GLOBAL_HOOK__
+          !(window as any).__APOLLO_DEVTOOLS_GLOBAL_HOOK__ &&
+          /^(https?|file):$/.test(window.location.protocol)
         ) {
           const nav = window.navigator;
           const ua = nav && nav.userAgent;