diff --git a/clang/include/clang/StaticAnalyzer/Core/PathSensitive/SMTConstraintManager.h b/clang/include/clang/StaticAnalyzer/Core/PathSensitive/SMTConstraintManager.h
index bf18c353b85083..5766af1fc78a4f 100644
--- a/clang/include/clang/StaticAnalyzer/Core/PathSensitive/SMTConstraintManager.h
+++ b/clang/include/clang/StaticAnalyzer/Core/PathSensitive/SMTConstraintManager.h
@@ -278,6 +278,11 @@ class SMTConstraintManager : public clang::ento::SimpleConstraintManager {
     if (const SymbolCast *SC = dyn_cast<SymbolCast>(Sym))
       return canReasonAbout(SVB.makeSymbolVal(SC->getOperand()));
 
+    // UnarySymExpr support is not yet implemented in the Z3 wrapper.
+    if (isa<UnarySymExpr>(Sym)) {
+      return false;
+    }
+
     if (const BinarySymExpr *BSE = dyn_cast<BinarySymExpr>(Sym)) {
       if (const SymIntExpr *SIE = dyn_cast<SymIntExpr>(BSE))
         return canReasonAbout(SVB.makeSymbolVal(SIE->getLHS()));
diff --git a/clang/test/Analysis/z3-unarysymexpr.c b/clang/test/Analysis/z3-unarysymexpr.c
new file mode 100644
index 00000000000000..ed9ba72468422e
--- /dev/null
+++ b/clang/test/Analysis/z3-unarysymexpr.c
@@ -0,0 +1,15 @@
+// RUN: %clang_analyze_cc1 -analyzer-checker=core,debug.ExprInspection -verify %s \
+// RUN:  -analyzer-constraints=z3 
+
+// REQUIRES: Z3
+//
+// Previously Z3 analysis crashed when it encountered an UnarySymExpr, validate
+// that this no longer happens.
+//
+
+// expected-no-diagnostics
+int negate(int x, int y) {
+  if ( ~(x && y))
+    return 0;
+  return 1;
+}