diff --git a/Doc/c-api/type.rst b/Doc/c-api/type.rst
index ee76f52289387f..f332e47d38a904 100644
--- a/Doc/c-api/type.rst
+++ b/Doc/c-api/type.rst
@@ -172,6 +172,10 @@ The following functions and structs are used to create
 
    .. versionadded:: 3.9
 
+   .. versionchanged:: 3.10
+
+      The function now accepts NULL ``tp_doc`` slot.
+
 .. c:function:: PyObject* PyType_FromSpecWithBases(PyType_Spec *spec, PyObject *bases)
 
    Equivalent to ``PyType_FromModuleAndSpec(NULL, spec, bases)``.
@@ -263,5 +267,3 @@ The following functions and structs are used to create
 
       The desired value of the slot. In most cases, this is a pointer
       to a function.
-
-      May not be ``NULL``.
diff --git a/Lib/test/test_capi.py b/Lib/test/test_capi.py
index 5150d5770f6644..a4928469881121 100644
--- a/Lib/test/test_capi.py
+++ b/Lib/test/test_capi.py
@@ -398,6 +398,13 @@ def __del__(self):
             del L
             self.assertEqual(PyList.num, 0)
 
+    def test_heap_ctype_doc_and_text_signature(self):
+        self.assertEqual(_testcapi.HeapDocCType.__doc__, "somedoc")
+        self.assertEqual(_testcapi.HeapDocCType.__text_signature__, "(arg1, arg2)")
+
+    def test_null_type_doc(self):
+        self.assertEqual(_testcapi.NullTpDocType.__doc__, None)
+
     def test_subclass_of_heap_gc_ctype_with_tpdealloc_decrefs_once(self):
         class HeapGcCTypeSubclass(_testcapi.HeapGcCType):
             def __init__(self):
diff --git a/Misc/NEWS.d/next/C API/2020-11-03-19-47-06.bpo-41832.dL1VJJ.rst b/Misc/NEWS.d/next/C API/2020-11-03-19-47-06.bpo-41832.dL1VJJ.rst
new file mode 100644
index 00000000000000..e0bce54eb93648
--- /dev/null
+++ b/Misc/NEWS.d/next/C API/2020-11-03-19-47-06.bpo-41832.dL1VJJ.rst	
@@ -0,0 +1,2 @@
+The :c:func:`PyType_FromModuleAndSpec` function now accepts NULL ``tp_doc``
+slot.
diff --git a/Modules/_testcapimodule.c b/Modules/_testcapimodule.c
index 54c1e62a282414..a1b736505d0a1d 100644
--- a/Modules/_testcapimodule.c
+++ b/Modules/_testcapimodule.c
@@ -6215,6 +6215,47 @@ static PyTypeObject MethodDescriptor2_Type = {
     .tp_flags = Py_TPFLAGS_DEFAULT | Py_TPFLAGS_BASETYPE | Py_TPFLAGS_HAVE_VECTORCALL,
 };
 
+PyDoc_STRVAR(heapdocctype__doc__,
+"HeapDocCType(arg1, arg2)\n"
+"--\n"
+"\n"
+"somedoc");
+
+typedef struct {
+    PyObject_HEAD
+} HeapDocCTypeObject;
+
+static PyType_Slot HeapDocCType_slots[] = {
+    {Py_tp_doc, (char*)heapdocctype__doc__},
+    {0},
+};
+
+static PyType_Spec HeapDocCType_spec = {
+    "_testcapi.HeapDocCType",
+    sizeof(HeapDocCTypeObject),
+    0,
+    Py_TPFLAGS_DEFAULT,
+    HeapDocCType_slots
+};
+
+typedef struct {
+    PyObject_HEAD
+} NullTpDocTypeObject;
+
+static PyType_Slot NullTpDocType_slots[] = {
+    {Py_tp_doc, NULL},
+    {0, 0},
+};
+
+static PyType_Spec NullTpDocType_spec = {
+    "_testcapi.NullTpDocType",
+    sizeof(NullTpDocTypeObject),
+    0,
+    Py_TPFLAGS_DEFAULT,
+    NullTpDocType_slots
+};
+
+
 PyDoc_STRVAR(heapgctype__doc__,
 "A heap type with GC, and with overridden dealloc.\n\n"
 "The 'value' attribute is set to 10 in __init__.");
@@ -6883,6 +6924,20 @@ PyInit__testcapi(void)
     Py_INCREF(TestError);
     PyModule_AddObject(m, "error", TestError);
 
+    PyObject *HeapDocCType = PyType_FromSpec(&HeapDocCType_spec);
+    if (HeapDocCType == NULL) {
+        return NULL;
+    }
+    PyModule_AddObject(m, "HeapDocCType", HeapDocCType);
+
+    /* bpo-41832: Add a new type to test PyType_FromSpec()
+       now can accept a NULL tp_doc slot. */
+    PyObject *NullTpDocType = PyType_FromSpec(&NullTpDocType_spec);
+    if (NullTpDocType == NULL) {
+        return NULL;
+    }
+    PyModule_AddObject(m, "NullTpDocType", NullTpDocType);
+
     PyObject *HeapGcCType = PyType_FromSpec(&HeapGcCType_spec);
     if (HeapGcCType == NULL) {
         return NULL;
diff --git a/Objects/typeobject.c b/Objects/typeobject.c
index acbe3fa3b5a7f1..066ec826905fb7 100644
--- a/Objects/typeobject.c
+++ b/Objects/typeobject.c
@@ -3015,6 +3015,10 @@ PyType_FromModuleAndSpec(PyObject *module, PyType_Spec *spec, PyObject *bases)
         else if (slot->slot == Py_tp_doc) {
             /* For the docstring slot, which usually points to a static string
                literal, we need to make a copy */
+            if (slot->pfunc == NULL) {
+                type->tp_doc = NULL;
+                continue;
+            }
             const char *old_doc = _PyType_DocWithoutSignature(type->tp_name, slot->pfunc);
             size_t len = strlen(old_doc)+1;
             char *tp_doc = PyObject_MALLOC(len);